Dr. Denese Wrinkle RX 76% Peptide Solution Concentrate 1 oz – Supports Smoother, Firmer-Looking Skin With Lightweight Hydration – Doctor-Developed Formula for Refined, Youthful-Looking Tone

Price: $99.00
(as of Jun 13, 2026 12:22:50 UTC – Details)

Product description

Comparison Table

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Customer Reviews

4.4 out of 5 stars 38

4.8 out of 5 stars 23

4.5 out of 5 stars 47

5.0 out of 5 stars 1

4.4 out of 5 stars 4

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Price

$99.00$99.00

$59.99$59.99

$54.00$54.00

$79.00$79.00

$60.00$60.00

$43.00$43.00

Formula Strength

Clinical Potency

Pro Strength

Triple Strength

Advanced Bio-Tech

Professional Grade

15% Acid Blend

Application

Serum / Pre-Cream

Pre-Moisturizer

Mix in or Solo

AM/PM Moisturizer

Mix Paste + Drops

Cotton pad/Leave-on

Best For

Deep Lines & Wrinkles

Severe Dryness

Slackening Skin

Barrier Repair

Dull, Rough Skin

Congestion

Benefit

Visibly relaxes lines

Locks in hydration

Visibly firms

Deep hydration

Resurfaces texture

Resurfaces & Clears

Skin Concerns

Dynamic Wrinkles

Dehydrated Skin

Loss of Firmness

Compromised Barrier

Uneven Tone

Pores, Roughness

Texture

Liquid Serum

Silky Gel-Serum

Liquid Drops

Light Cream

Paste + Liquid

Liquid

Key Ingredients

76% Peptides

Retinol, Ceramides

Peptides, Retinol

Ceramides, Lipids

Vit C, Glycolic Acid

Glycolic, Salicylic

Visible Results

Smooths look of lines

Plump, dewy skin

More elastic feel

Smooth, supple feel

Glass-like radiance

Clearer, smoother

Shelf Life

24M Sealed, 12M Open

24M Sealed, 12M Open

24M Sealed, 12M Open

24M Sealed, 12M Open

24M Sealed, 12M Open

24M Sealed, 12M Open

How does this peptide solution help improve the look of lines and skin texture?

This multi peptide formula helps soften the look of fine lines and supports smoother, firmer-looking skin. The lightweight texture absorbs quickly, making it easy to use daily for a more polished and refreshed appearance.

Can I use this around my eyes for visible lines or a tired appearance?

Yes, apply a small amount around the orbital bone to support smoother, firmer-looking skin. The lightweight texture works well with eye creams and makeup, helping the area look more refreshed without feeling heavy.

How quickly can I expect to see visible changes in my skin’s appearance?

Many users notice smoother, more hydrated-looking skin within days. With consistent daily use, the look of texture and fine lines improves over time as the multi peptide blend supports a more refined, refreshed appearance.

Should I use this product in the morning, at night, or both for best results?

Use it morning or evening on clean skin. It layers smoothly under SPF, makeup, or night creams, making it easy to fit into any routine while supporting a smoother-looking, more balanced finish with steady use.

Can this be paired with other skincare products like moisturizers or eye creams?

Yes, apply it first, then follow with moisturizer or eye serum. The lightweight texture absorbs quickly to help products layer comfortably, supporting a smoother-looking finish without disrupting your existing skincare steps.

Is Discontinued By Manufacturer ‏ : ‎ No
Package Dimensions ‏ : ‎ 8.5 x 2.32 x 1.65 inches; 1 ounces
UPC ‏ : ‎ 811684020907
Manufacturer ‏ : ‎ Dr. Denese
ASIN ‏ : ‎ B00DLNXWHQ
Best Sellers Rank: #407,697 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #7,563 in Facial Serums
Customer Reviews: 4.4 4.4 out of 5 stars (38) var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
FIRMING PEPTIDE POWER: This multi-peptide concentrate supports smoother, firmer-looking skin by refining visible texture and enhancing a more sculpted, confident appearance along the neck, chin, and jawline with consistent daily use.
SMOOTHER, BRIGHTER-LOOKING SKIN: Helps soften the look of wrinkles and visible lines while supporting a radiant, refreshed appearance, improving the look of tired or dull areas & fitting easily into a mature routine focused on smoother-looking skin.
FAST-ABSORBING HYDRATION: This lightweight formula absorbs quickly and layers cleanly under moisturizer or makeup, offering smooth glide and balanced hydration without heaviness for both morning and evening use in any daily skincare routine.
UNDER-EYE SUPPORT: Targets the delicate under-eye area to help soften visible lines and support smoother, firmer-looking skin, pairing seamlessly with your preferred eye treatments to enhance a refreshed, awake appearance with consistent daily use.
CONSISTENT RESULTS WITH LESS PRODUCT: This concentrated formula helps your skincare routine feel more efficient as it supports softer, refined-looking skin over time, delivering performance-driven benefits with just a small amount used each day.

Product summary

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